Eftychios is an Associate Professor of Computer Sciences at the University of Wisconsin-Madison, which he joined in January 2011. Prior to that, from 2007 to 2010, he was a post-doctoral researcher at the University of California, Los Angeles, jointly appointed to the departments of Mathematics and Computer Science. He obtained his PhD degree in Computer Science from Stanford University in 2007, and BSc degrees in Computer Sciences and Mathematics in 2000 and 2002, respectively, from the University of Crete, Greece.

His current research revolves around computer graphics, physics-based modeling/simulation and scientific computing. He is particularly interested in the development of algorithms and numerical techniques that can facilitate the efficient and accurate simulation of part s of the human body, with focus on applications in biomechanics and virtual surgery.